Drug-Like Properties, Second Edition: Concepts, Structure Design and Methods from ADME to Toxicity Optimization

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Drug-Like Properties, Second Edition: Concepts, Structure Design and Methods from ADME to Toxicity Optimization

Author :
Rating : 4.36 (557 Votes)
Asin : 0128010762
Format Type : paperback
Number of Pages : 580 Pages
Publish Date : 2014-07-02
Language : English

DESCRIPTION:

Building on those foundations, this thoroughly updated revision covers a wide variety of current methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties for process and product improvement. Through valuable case studies, structure-property relationship descriptions, and structure modification strategies, Drug-Like Properties, Second Edition, offers tools and methods for ADME/Tox scientists through all aspects of drug research, discovery, design, development, and optimization.Provides a comprehensive and valuable working handbook for scientists and students in medicinal chemistryIncludes expanded coverage of pharmacokinetics fundamentals and effectsContains updates throughout, including the authors’ recent work in the importance of solubility in drug development; new and currently used property meth

About the Author Li Di is an Associate Research Fellow at Pfizer, USA

Li Di is an Associate Research Fellow at Pfizer, USA

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