The Philadelphia Chromosome: A Mutant Gene and the Quest to Cure Cancer at the Genetic Level
| Author | : | |
| Rating | : | 4.38 (587 Votes) |
| Asin | : | B00C7DXYHY |
| Format Type | : | |
| Number of Pages | : | 466 Pages |
| Publish Date | : | 2017-07-18 |
| Language | : | English |
DESCRIPTION:
It is an astonishing tale that will provide victims of other cancers and their loved ones realistic hope that cures may yet be found in their lifetimes. Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML). The Philadelphia Chromosome charts the milestones that led to present-day cancer treatment and tells the inspiring story of the dedicated men and women who, working individually and in concert, have sought to plum the mysteries of the human genome in order to conquer those deadly and most feared diseases called cancer.
"Fascinating book about the advent of Gleevec" according to Rae. This book was well written and understandable to a non-scientist, such as myself. That is not to say, however, that I wasn't sometimes confused about how all the different people whose discoveries came together to lead to the discovery of Gleevec fit together. The author jumps back and forth . kidshearts said I have good news and bad news. Fascinating story of the long, circuitous road from the discovery of a genetic marker for chronic myeloid leukemia to the development of an imperfect, specific treatment. It required 50 years, dozens of unconnected researchers, starts and stops and blind alleys before anything related to pati. Well-written and interesting history of targeted therapy for a specific leukemia P. McCarthy This is a well written book which I Iistened to as an audio book. It is difficult to write about history when many of the principals are still alive, in this case as still active as basic science and clinical science researchers. However Ms. Wapner gets it right regarding the history of chron